Challenges and updates about MRSA that you need to know

 




MRSA testing San Diego in California (CA)continues to be important as MRSA continues to be one of the most common causes of community-acquired infections throughout the world. Whilst its incidence has been reduced by about 31%, MRSA is still prevalent and a public problem.

Finding the optimal antibiotic therapy for this infection is a great challenge. Whilst vancomycin has been a top therapeutic agent for infections related to MRSA for over 50 years, there has been a big concern with its efficacy. Here are some challenges about updates about MRSA.

Choosing the right drug

Trends of increasing MIC for vancomycin together with the emergency of VISA, hVISA, and VRSA isolates challenge vancomycin’s effectiveness. Although vancomycin is an agent with the biggest communicative experience for MRSA, professionals suggest that alternative agents should be used for isolates.

Choosing the right dose

After MRSA testing, it is crucial to choose the right dose if infections are present. Whilst we are familiar with the usual dosing of the MRSA antibiotics, determining the best dosing in overweight patients is a big challenge that we have to face. There has been a big interest in the pharmacokinetic differences of some MRSA agents in obesity settings.

Treatment duration

The treatment duration for MRSA infections is controversial. For example, MRSA pneumonia has a wide recommended duration of about seven days to twenty-one days. This is largely based on expert opinion. Bacteremias that are uncomplicated are recommended to be treated for at least two weeks.

Research has found that shorter treatment durations lead to high rates of relapsed infections. Pharmacists play an important role in choosing alternative agents for MRSA infections treatment given their expertise in the pharmacokinetic characteristics and differential pharmacodynamics, ultimately choosing the right drug and its recommended duration, dose and monitoring parameters for each patient after an MRSA testing San Diego CA proves that they have been infected.

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